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Comazzetto, Stefano (2009) In vitro effect of retinoic acid and epigenetic modifying drugs on mesenchymal stem cells. [Laurea specialistica biennale]

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Abstract

Effetto in vitro dell'acido retinoico e dei farmaci epigenetici sulle cellule staminali mesenchimali

Tipologia del documento:Laurea specialistica biennale
Corsi di Laurea specialistica biennale:Facoltà di Scienze MM. FF. NN. > Biologia molecolare
Parole chiave:Mesenchymal, Cellule staminali, Retinoic acid, Acido retinoico, Self-renewal
Settori scientifico-disciplinari del MIUR:Area 05 - Scienze biologiche > BIO/06 Anatomia comparata e citologia
Codice ID:24321
Relatore:Bianchi, Vera
Data della tesi:2009
Biblioteca:Polo di Scienze > CIS "A. Vallisneri" - Biblioteca Biologico Medica
Tipo di fruizione per il documento:on-line per i full-text
Tesi sperimentale (Si) o compilativa (No)?:

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Abdallah BM, Kassem M Human mesenchymal stem cells: from basic biology to clinical Cerca con Google

applications. Gene Therapy 2008; 15: 109-116. Cerca con Google

Altucci L, Leibowitz MD, Ogilvie KM, de Lera AR, Gronemeyer H. RAR and RXR modulation in cancer and metabolic disease. Nature review drug discovery 2007; 6: 793-810. Cerca con Google

Alvarez S, Germain P, Alvarez R, Rodriguez-Barrios F, Gronemeyer H, de Lera AR. Structure, function and modulation of retinoic acid receptor beta, a tumor suppressor. The International Journal of Biochemistry and Cell Biology 2007; 39: 1406-1415. Cerca con Google

Bartholomew A, Sturgeon C, Siatskas M, Ferrer K, McIntosh K, Patil S, Hardy W, Devine S, Ucker D, Deans R, Moseley A, Hoffman R. Mesenchymal stem cells suppress lymphocyte proliferation in vitro and prolong skin graft survival in vivo. Experimental Hematology 2002; 30: 42-48. Cerca con Google

Boyer LA, Lee TI, Cole MF, Johnstone SE, Levine SS, Zucker JP, Guenther MG, Kumar RM, Murray HL, Jenner RG, Gifford DK, Melton DA, Jaenisch R, Young RA. Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 2005; 122: 947-56. Cerca con Google

Caplan AI. Adult mesenchymal stem cells for tissue engineering versus regenerative medicine. Journal of Cellular Physiology 2007; 213: 341-347. Cerca con Google

Chambon P. A decade of molecular biology of retinoic acid receptors. FASEB Journal 1996; 10: 940-954. Cerca con Google

Chen L, Daley GQ. Molecular basis of pluripotency. Human molecular genetics 2008; 17: 23-27. Cerca con Google

Cho HH, Park HT, Kim YJ, Bae YC, Suh KT, Jung JS. Induction of osteogenic differentiation of human mesenchymal stem cells by histone deacetylase inhibitors. Journal of Cellular Biochemistry 2005; 96: 533-542. Cerca con Google

Chomienne C, Balitrand N, Ballerini P, Castaigne S, de The H, Degos L. All-trans retinoic acid modulates the retinoic acid receptor-a in promyelocytic cells. Journal of clinical Investigation 1991; 88: 2150-2154. Cerca con Google

Chomienne C, Ballerini P, Balitrand N, Amar M, Bernard JF, Boivin P, Daniel MT, Berger R, Castaigne S, Degos L. Retinoic acid therapy for promyelocytic leukaemia. Lancet 1989; 2: 746-747. Cerca con Google

Di Bernardo G, Squillaro T, Dell’Aversana C, Miceli M, Cipollaro M, Cascino A, Altucci L, Galderisi U. Histone deacetylase inhibitors promote apoptosis and senescence in human mesenchymal stem cells. Stem Cells and Development 2009; 18: 573-581. Cerca con Google

Di Croce L, Raker VA, Corsaro M, Fazi F, Fanelli M, Faretta M, Fuks F, Lo Coco F, Kouzarides T, Nervi C, Minucci S, Pelicci PG. Methyltransferase recruitment and DNA hypermethylation of target promoters by an oncogenic transcription factor. Science 2002; 295: 1079-1082. Cerca con Google

Dominici M, Le Blanc K, Mueller I, Slaper-Contenbach I, Marini F, Krause D, Deans R, Keating A, Prockop D, Hortiwitz E. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 2006; 8: 315-317. Cerca con Google

Ferrara FF, Fazi F, Bianchini A, Padula F, Gelmetti V, Minucci S, Mancini M, Pelicci PG, Lo Coco F, Nervi C. Histone deacetylase-targeted treatment restores retinoic acid signaling and differentiation in acute myeloid leukemia. Cancer research 2001; 61: 2-7. Cerca con Google

Folberg A, Nagy Kovacs E, Luo J, Giguere V, Featherstone MS. RARbeta mediates the response of Hoxd4 and Hoxb4 to exogenous retinoic acid. Developmental Dynamics 1999; 215: 96-107. Cerca con Google

Friedenstein AJ, Shapiro-Piatetzky II, Petrakova KV. Osteogenesis in transplants of bone marrow cells. Journal of embryology and experimental morphology 1966; 16: 381-390. Cerca con Google

Friedenstein AJ, Chailakhyan RK, Gerasimov UV. Bone marrow osteogenic stem cells: in vitro cultivation and transplantation in diffusion chambers. Cell and tissue kinetics 1987; 20: 263-272. Cerca con Google

Friedenstein AJ. Osteogenic stem cells in bone marrow. In Bone and Mineral Research, J.N.M. Heersche and J.A. Kanis, eds. 1990; pp. 243-272. Cerca con Google

Germain P, Chambon P, Eichele G, Evans RM, Lazar MA, Leid M, De Lera AR, Lotan R, Mangelsdorf DJ, Gronemeyer H. International Union of Pharmacology. LX. Retinoic Acid Receptors. Pharmacologiacl Review 2006; 58: 712-725. Cerca con Google

Germain P, Chambon P, Eichele G, Evans RM, Lazar MA, Leid M, De Lera AR, Lotan R, Mangelsdorf DJ, Gronemeyer H. International Union of Pharmacology. LXIII. Retinoid X Receptors. Pharmacologiacl Review 2006; 58: 760-772. Cerca con Google

Grignani F, De Matteis S, Nervi C, Tomassoni L, Gelmetti V, Cioce M, Fanelli M, Ruthardt M, Ferrara FF, Zamir I, Seiser C, Grignani F, Lazar MA, Minucci S, Pelicci PG. Fusion protein of the retinoic acid receptor-α recruit hystone deacetylase in promyelocytic leukemia. Nature 1998; 391: 815-818. Cerca con Google

Gronthos S, Graves SE, Ohta S, Simmons PJ. The STRO-1+ fraction of adult human bone marrow contains the osteogenic precursor. Blood 1994; 84: 4164-4173. Cerca con Google

Guidez F, Huang W, Tong JH, Dubois C, Balitrand N, Waxman S, Michaux JL, Martiat P, Degos L, Chen Z, et al. Poor response to all-trans retinoic acid therapy in a t(11;17) PLZF/RAR alpha patient. Leukemia 1994; 8; 312-317. Cerca con Google

Kafienah W, Mistry S, Perry MJ, Politopoulou G, Hollander AP. Pharmacological regulation of adult stem cells: chondrogenesis can be induced using a synthetic inhibitor of the retinoic acid receptor. Stem Cells 2007; 25: 2460-2468. Cerca con Google

Kiel MJ, Morrison SJ. Maintaining hematopoietic stem cells in the vascular niche. Immunity 2006; 25: 862-864. Cerca con Google

Kuznetsov SA, Krebsbach PH, Satomura K, Kerr J, Riminucci M, Benayahu D, Robey PG. Single-colony derived strains of human marrow stromal fibroblast form bone after transplantation 􀀀__􀀀_. Journal of bone and mineral research 1997; 12: 1335-1347. Cerca con Google

Lazennec G, Jorgensen C. Concise review: adult multipotent stromal cells and cancer: risk or benefit? Stem Cell 2008; 26: 1387-1394. Cerca con Google

Le Blanc K, Gotherstrom C, Tammik C, Ringden O. HLA expression and immunologic properties of differentiated and unidifferentiated adult and fetal mesenchymal stem cells. Bone Marrow Transplant 2003; 31: S244-245. Cerca con Google

Lee TI, Jenner RG, Boyer LA, Guenther MG, Levine SS, Kumar RM, Chevalier B, Johnstone SE, Cole MF, Isono K, Koseki H, Fuchikami T, Abe K, Murray HL, Zucker JP, Yuan B, Bell GW, Herbolsheimer E, Hannett NM, Sun K, Odom DT, Otte AP, Volkert TL, Bartel DP, Melton DA, Gifford DK, Jaenisch R, Young RA. Control of developmental regulators by Polycomb in human embryonic stem cells. Cell 2006; 125:301-13. Cerca con Google

Li Y, Hashimoto Y, Agadir A, Kagechika H, Zhang X. Identification of a novel class of retinoic acid receptor beta-selective retinoid antagonists and their inhibitory effects on AP-1 activity and retinoic acid-induced apoptosis in human breast cancer cells. The Journal of biological chemistry 1999; 274: 15360-15366. Cerca con Google

Loh YH, Wu Q, Chew JL, Vega VB, Zhang W, Chen X, Bourque G, George J, Leong B, Liu J, Wong KY, Sung KW, Lee CW, Zhao XD, Chiu KP, Lipovich L, Kuznetsov VA, Robson P, Stanton LW, Wei CL, Ruan Y, Lim B, Ng HH. The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nature Genetics 2006; 38: 431-40. Cerca con Google

Loh YH, Ng JH, Ng HH. Molecular framework underlying pluripotency. Cell cycle 2008; 7: 885-891 Cerca con Google

Nagpal S, Zelent A, Chambon P. RAR-beta4, a retinoic acid receptor isoform is generated from RAR-beta 2 by alternative splicing and usage of a CUG initiating codon. Proceeding of the National Academy of Science 1992; 89: 2718-2722. Cerca con Google

Nagy L, Kao HY, Chakravarti D, Lin RJ, Hassig CA, Ayer DE, Schreiber SL, Evans RM. Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase. Cell 1997; 89: 373-380. Cerca con Google

Niwa H. Molecular mechanism to maintain stem cell self-renewal of ES cells. Cell structure and function 2001; 26: 137-148. Cerca con Google

Okazawa H. Okamoto K, Ishino F, Ishino-Kaneko T, Takeda S, Toyoda Y, Muramatsu M, Hamada H. The oct3 gene, a gene for an embryonic transcription factor, is controlled by a retinoic acid repressible enhancer. The EMBO Journal 1991; 10:2997-3005. Cerca con Google

Oliva A, Borriello A, Zeppetelli S, Di Feo A, Cortellazzi P, Ventriglia V, Criscuolo M, Zappia V, Della Ragione F. Retinoic acid inhibits the growth of bone marrow mesenchymal stem cells and induces p27Kip1 and p16INK4A up-regulation. Molecular and cellular Biochemistry 2003; 247: 55-60. Cerca con Google

Perissi V, Rosenfeld MG. Controlling nuclear receptors. The circular logic of cofactor cycles. Nature review Molecular Cell Biology 2005; 6: 542-554. Cerca con Google

Petite H, Viateau V, Bensaid W, Meunier A, de Pollak C, Bourguignon M, Oudina K, Sedel L, Guillemin G. Tissue-engineered bone regeneration. Nature Biothecnology 2000; 18: 959-963. Cerca con Google

Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, Moorman MA, Simonetti DW, Craig S, Marshak DR. Multilineage potential of adult human mesenchymal stem cells. Science 1999; 284; 143-147. Cerca con Google

Piu F, Gauthier NK, Olsson R, Currier EA, Lund BW, Croston GE, Hacksell U, Brann MR. Identification of novel subtype selective RAR agonists. Biochemical pharmacology 2005; 71: 156-162. Cerca con Google

Privalsky ML. Regulation of SMRT and N-CoR corepressor function. Current Topics in microbiology and immunology 2001; 254: 117-136. Cerca con Google

Purton LE, Dworkin S, Olsen GH, Walkley CR, Fabb SA, Collins SJ, Chambon P. RARγ is critical for maintaining a balance between hematopoietic stem cell self-renewal and differentiation. The Journal of Experimental Medicine 2006; 203; 1283-1293. Cerca con Google

Ringden O, Uzunel M, Rasmusson I, Remberger M, Sundberg B, Lonnies H, Marschall HU, Dlugosz A, Szakos A, Hassan Z, Omazic B, Aschan J, Barkholt L, Le Blanck K. Mesenchymal stem cells for treatment of therapy-resistant graft-versus-host disease. Transplantation 2006; 81: 1390-1397. Cerca con Google

Sacchetti B, Funari A, Michienzi S, Di Cesare S, Piersanti S, Saggio I, Tagliafico E, Ferrari S, Robey PG, Riminucci M, Bianco P. Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment. Cell 2007; 131: 324-336. Cerca con Google

Schoorlemmer J, van Puijenbroeck A, van den Eijnden M, Jonk L, Pals C, Kruijer W. Characterization of a negative retinoic acid response element in the murine Oct4 promoter. Molecular and Cellular Biology 1993; 14: 1122-1136. Cerca con Google

Sekiya I,Larson BL, Smith JR, Prochampally R, Cui JG, Prockop DJ. Expansion of human adult stem cells from bone marrow stroma: conditions that maximize the yields of early progenitors and evaluate their quality. Stem Cells 2002; 20: 530-541. Cerca con Google

Serpente P, Tumpel S, Ghyselinck NB, Niederreither K, Wiedemann LM, Dolle P, Chambon P, Krumlauf R, Gould AP. Direct crossregulation between retinoic acid receptor β and Hox genes during hindbrain segmentation. Development 2004; 132: 503-513. Cerca con Google

Sirchia SM, Ren M, Pili R, Sironi E, Somenzi G, Ghidoni R, Toma S, Nicolo G, Sacchi N. Endogenous reactivation of the RARbeta2 tumor suppressor gene epigenetically silenced in breast cancer. Cancer research 2002; 62: 2455-61. Cerca con Google

Soprano DR, Teets BW, Soprano KJ. Role of retinoic acid in the differentiation of embryonal carcinoma and embryonic stem cells. Vitamons and Hormones 2007; 75: 69-85. Cerca con Google

Soriano AO, Yang H, Faderl S, Estrov Z, Giles F, Ravandi F, Cortes J, Wierda WG, Ouzounian S, Quezada A, Pierce S, Estey EH, Issa JJ, Kantarjian HM, Garcia-Manero G. Safety and clinical activity of the combination of 5-azacytidine, valproic acid, and all-retinoic acid in acute myeloid leukemia and myelodisplastic syndrome. Blood 2007; 110: 2302-2308. Cerca con Google

Solchaga LA, Temenoff JS, Gao J, Mikos AG, Caplan AI, Goldberg VM. Repair of osteochondral defects with hyaluronan- and polyester-based scaffolds. Osteoarthritis Cartilage 2005; 13: 297-309. Cerca con Google

Tay Y, Zhang J, Thomson AM, Lim B, Rigoutsos I. MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation. Nature 2008; 455: 1124-1130. Cerca con Google

Wan DC, Siedhoff MT, Kwan MD, Nacamuli RP, WU BM, Longaker MT. Refining retinoic acid stimulation for osteogenic differentiation of murine adipose-derived adult stromal cells. Tissue Engineering 2007; 7: 1623-1631. Cerca con Google

Wang, J., Rao, S., Chu, J., Shen, X., Levasseur, D.N., Theunissen, T.W. and Orkin, S.H. A protein interaction network for pluripotency of embryonic stem cells. Nature 2006; 444: 364–368. Cerca con Google

Xu W, Zhang X, Qian H, Zhu W, Sun X, Hu J, Zhou H, Chen JC. Mesenchymal Stem Cells from Adult Human Bone Marrow Differentiate into a Cardiomyocyte Phenotype In Vitro. Experimental Biology and Medicine 2004; 229: 623–631. Cerca con Google

Xu XC, Lee JJ, Wu TT, Hoque A, Ajani JA, Lippman SM. Increased retinoic acid receptorbeta4 correlates in vivo with reduced retinoic acid receptor-beta2 in esophageal squamous cell carcinoma. Cancer Epidemiology, biomarker and prevention 2005; 14: 826-829. Cerca con Google

Xu XC. Tumor-suppressor activity of retinoic acid receptor-β in cancer. Cancer Letters 2007; 253: 14-24. Cerca con Google

Yamanaka S, Takahashi K. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006; 126: 663-676. Cerca con Google

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