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Bonafè, Giulia (2010) A G-rich sequence within the 3'UTR of KiSS1 forms G-quadruplex. [Magistrali biennali]

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Abstract

L’obiettivo dello studio è stato quello di dimostrare che la regione ricca in guanine del 3’UTR del gene KiSS1 forma effettivamente strutture secondarie G-quadruplex e di capire se i polimorfismi trovati nei pazienti affetti da pubertà precoce interferiscono con la formazione di queste strutture e quindi con la regolazione del gene. È stato anche iniziato uno studio preliminare sulle potenziali interazioni tra proteine e i G-quadruplex di KiSS1.

Item Type:Magistrali biennali
Corsi di Diploma di Laurea:Scuola di Scienze > Biologia sanitaria
Uncontrolled Keywords:G-quadruplex, Pubertà precoce
Subjects:Area 05 - Scienze biologiche > BIO/18 Genetica
Codice ID:26714
Relatore:Tiso, Natascia
Correlatore:de Roux, Nicolas
Data della tesi:2010
Biblioteca:Polo di Scienze > CIS "A. Vallisneri" - Biblioteca Biologico Medica
Tipo di fruizione per il documento:on-line per i full-text
Tesi sperimentale (Si) o compilativa (No)?:Yes

Bibliografia

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