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Intelvi, Marco (2010) Contact drying of particulate pharmaceuticals: modelling and simulation. [Magistrali biennali]

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In order to give a concrete response to the need of predictive contact drying simulation tools in pharmaceutical industry, simulation programs for contact drying of pharmaceutical powders were developed in this thesis work. These are two programs for simulate the two main contact drying operation conditions used in the pharmaceutical industry: vacuum and atmospheric contact drying of agitated beds. The programs give a predictive estimation of drying rate curve and bulk bed temperature during contact drying. Only initial conditions, operating conditions, geometrical data, type of substances, solid phase properties and two parameter for the evaluation of an empirical mixing coefficient, are required as input data. A first validation of the developed programs was made on experimental data from literature, regarding two common pharmaceutical excipient powders, wetted with water and dried in a disc contact dryer. The simulation results show a good agreement with the experimental data

Item Type:Magistrali biennali
Corsi di Diploma di Laurea:Scuola di Ingegneria > Ingegneria Chimica e dei Processi Industriali
Scuola di Ingegneria > Ingegneria Chimica e dei Processi Industriali
Uncontrolled Keywords:contact drying, particulate bed, modelling, drying technology, pharmaceuticals
Subjects:Area 09 - Ingegneria industriale e dell'informazione > ING-IND/27 Chimica industriale e tecnologica
Codice ID:26815
Relatore:Canu, Paolo
Correlatore:Joaquin, Martinez
Data della tesi:10 December 2010
Biblioteca:Polo di Ingegneria > Biblioteca Centrale di Ingegneria
Tipo di fruizione per il documento:on-line per i full-text
Tesi sperimentale (Si) o compilativa (No)?:Yes

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