Abstract

Tandem repeat proteins form a distinct class of structures of great relevance due to their connection to neurodegenerative diseases and their functions in human health. Starting from RAPHAEL, a solenoid detection tool, a new method is devised.The principal aim of this work is the upgrade of RAPHAEL to achieve a deeper level of classification of tandem repeats. RAPHAEL2.0 demonstrates to obtain good performances in detection and prediction of different classes of repeats.