Fanchin, Francesco (2016) Crescita di colonie batteriche bioluminescenti: ottimizzazione di modelli teorici. [Laurea triennale]
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Single colony bacterial cells communicate with each other on the basis of Quorum Sensing (QS) mechanism, being capable to organize collective behaviour like bioluminescence. In a typical QS mechanism, bacteria provide signal molecules production; above a certain threshold concentration, a consistent fraction of signal molecules binds herselves to receptors on the surface of bacteria, triggering a new phenotype, e.g. bioluminescence, through a cascade of cellular signals. Aim of this thesis is reproducing bioluminescence experimental curves by means of a simplified model; with a suitable combination of deterministic and stochastic algorithms, parameters included in it will be optimized minimizing difference between experimental data and theoretical previsions.
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