Veronese, Sofia (2017) Designe and syntesis of novel inhibitors of norovirus polymerase. [Magistrali a ciclo unico]
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Starting from the structure of two compounds, the aim of this project was to synthesize a series of new derivates to explore the antiviral potential associated with the original scaffold. After synthesis, all new compounds were analysez with molcular dooking studies, to evaluate their binding mode to RDRP.
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