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Agnolon, Marco (2018) Ecology of cancer: an evolutionary game theory approach to model cancer growth. [Laurea triennale]

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Abstract

In the thesis we focus on multiple myeloma bone disease. In this cancer three types of cells are present. Among the different groups of cells, we will identify two groups of cells that we will call "residents" that are healthy cells normally present in the body -i.e. osteoblast (OB) and osteoclast (OC) -, and a third group of mutant malignant cells (MM) - i.e. the tumor - that we call "invaders" that tries to replace the osteoblasts. The aim is to analyze a deterministic model of the dynamics of the evolution of these three types of cells and explore the effects of different interaction networks among cell groups. Main theoretical tool for our analysis will be Evolutionary Game Theory (EGT).

Item Type:Laurea triennale
Corsi di Laurea Triennale:Scuola di Scienze > Fisica
Uncontrolled Keywords:evolutionary game theory of cancer, multiple myeloma, cancer dynamics, replicator cell dynamics; cancer ecology
Subjects:Area 02 - Scienze fisiche > FIS/07 Fisica applicata (a beni culturali, ambientali, biologia e medicina)
Codice ID:61199
Relatore:Formentin, Marco
Correlatore:Tovo, Anna
Data della tesi:July 2018
Biblioteca:Polo di Scienze > Dip. Fisica e Astronomia "Galileo Galilei" - Biblioteca
Tipo di fruizione per il documento:on-line per i full-text
Tesi sperimentale (Si) o compilativa (No)?:No

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