Lo Riso, Valentina (2018) Evaluation of a new set of urolithin derivates as potential inhibitors of the human topoisomerase II enzyme. [Laurea specialistica a ciclo unico]
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Urolithins are natural derivates of ellagic acid. A new synthetic set of this metabolites were tested to asses their inhibitory activity on human topoisomerase IIa. Further evaluations are provide for structure-activity relationship and their mechanist of action.
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